HMG 75 IU Gen-Shi
HMG *Human menopozal gonadotropin* 75 IU GENSHI LABS. OSAKA JAPAN
Expiration date is printed wrong; it’s not 2020. It’s recomended to use before 07/2018
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Human menopausal gonadotropin (HMG) is usually taken to help induce ovulation for the purposes of IVF and IUI. Contain luteinizing hormone (LH) and follicle stimulating hormone (FSH), which are necessary for ovulation. HMG is extracted from the urine of postmenopausal women and is purified before being used.
Mechanism of action
Starts and regulates gametogenesis regulates the maturation of the follicle and corpus luteum formation in the ovary and spermatogenesis and development of interstitial tissue in the testicle.
Infertility in women with ovarian hypo-or normogonadotropic: stimulation of follicular growth. Induction of ovulation, followed or not by artificial insemination (anovulation, including polycystic ovary syndrome (PCOS)) in women who have not responded to the TTO. with clomiphene citrate. Controlled ovarian hyperstimulation to induce the development of multiple follicles in medically assisted reproduction techniques (in vitro fertilization embryo transfer (IVF / ET), gamete intra-fallopian transfer (GIFT) and inj. Intracytoplasmic sperm injection (ICSI), etc.. Infertility in men with hypogonadotropic hypo-or normogonadotrópico: In combination with hCG to stimulate spermatogenesis.
Anovulatory: commence within the initial 7 days of the menstrual cycle. Initial dose: 75-150 IU / day, 7 days. Adjust dose every 7 days according to individual response, dose increase: 37.5 IU per adjustment, not to exceed 75 IU. Max.: 225 IU / day. If no response in 4 weeks, leave cycle and start again with higher initial dose of interrupted cycle. When you get an optimal response, given an inj. only 5,000 to 10,000 IU hCG, 1 day after the last inj. of hMG. It is recommended to have intercourse the same day and the day after hCG administration. IUI can be performed alternately. Controlled ovarian hyperstimulation to induce the development of multiple follicles in medically assisted reproduction techniques: starting 2 weeks after starting tto. antagonist. Initial dose: 150-225 IU / day during the first 5 days of tto. Adjust according to individual response, not to exceed 150 IU per adjustment. Max.: 450 IU / day, no more than 20 days. When a number of follicles reach the appropriate size, given an inj. only up to 10,000 IU to induce final follicular maturation prior to oocyte retrieval. Control at least 2 weeks after administration of HCG.
Infertility in men: 1000-3000 IU of hCG initial 3 times / wk until serum testosterone level is normal. After IM administration 75-150 IU FSH + LH 75-150 IU / 3 times a week for several months.
Women: tumors in the hypothalamic-pituitary area, tumor in the uterus, ovaries or breasts, pregnancy and lactation, gynecological bleeding of unknown cause or increase in ovarian cysts caused by polycystic ovary syndrome, situations in which the result of tto. is rarely favorable: primary ovarian failure, malformation of sexual organs incompatible with pregnancy, fibroid uterus incompatible with pregnancy.
Men: prostate cancer, testicular tumors.
Warnings and Precautions
Risk of venous or arterial thromboembolic effects. During the title often occur multiple unwanted pregnancies. Risk of ectopic pregnancy in women with emph. Tubal. Monitoring of ovarian response. Risk of benign and malignant neoplasms in the female reproductive tract.
Contraindicated. Is not indicated in any way to treat pregnant women.
Is not indicated in any case to try breast-feeding women.
Commun second effects :
Abdominal pain, nausea, abdominal fullness, headache, OHSS, pelvic pain, reaction and pain at the injection site.
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